Sibutramine, once used as an appetite suppressant, gained attention as a fat burner due to its ability to aid weight loss by affecting neurotransmitters in the brain. However, it's essential to note that Sibutramine was withdrawn from many markets due to concerns about cardiovascular side effects. The use of Sibutramine as a fat burner should be approached with caution, and individuals should seek medical guidance to assess potential risks and explore safer alternatives for weight management.